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Antihistamines and Exercise: The Surprising Finding That Blocking Histamine Blunts Training Gains

2 days ago
4 min read

Most people think of histamine only as the thing that makes allergies miserable and antihistamines as harmless. The exercise physiology of the last decade has complicated that picture in a way that matters to anyone who trains: histamine released within working muscle is part of how the body reads an exercise session and builds the adaptations that follow, and the drugs that block it may quietly reduce the return on a training block.

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