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Citrulline Supplementation and Exercise Performance

5 days ago
4 min read

Citrulline is the pre-workout ingredient with the cleanest biochemistry: it converts to arginine in the kidney, arginine feeds nitric-oxide synthesis, and nitric oxide widens vessels. Oral arginine itself is mostly destroyed in the gut and liver, which is why citrulline replaced it. The mechanism holds up in the blood. The performance effect is another matter.

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