The Gut Microbiome and Obesity: What the Mice Proved, What the Human Trials Have Not - and Why Probiotics Are Not a Weight-Loss Pill

The idea that the bacteria in your gut decide how much fat you carry has moved from laboratory curiosity to supplement-aisle marketing in barely a decade. The laboratory part is real: transfer the gut bacteria of an obese mouse into a germ-free one and it gets fatter than a mouse given lean bacteria, on the same food. The marketing part is not: when the same logic is tested in humans with probiotic capsules, the results are small, strain-specific and inconsistent. Understanding both halves is the difference between a genuine mechanism of obesity and a product that borrows its credibility.

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